Ankylosing spondylitis is a chronic inflammatory disorder that affects the spine and joints. It is a type of arthritis that causes pain and stiffness in the lower back, hips, and shoulders. Over time, the affected areas become inflamed and stiff, which can lead to difficulty with movement and loss of flexibility. In some cases, the joints can fuse together, which is known as ankylosis. Ankylosing spondylitis is more common in men than women, and it usually affects people between the ages of 15 and 45. Symptoms can range from mild to severe and can include pain, stiffness, fatigue, inflammation, and difficulty moving. While there is no cure for ankylosing spondylitis, there are treatments available to help manage symptoms and improve quality of life. These treatments typically include medications, physical therapy, and lifestyle changes such as exercise, stretching, and stress reduction.